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ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data

BACKGROUND: Data from discovery proteomic and phosphoproteomic experiments typically include missing values that correspond to proteins that have not been identified in the analyzed sample. Replacing the missing values with random numbers, a process known as “imputation”, avoids apparent infinite fo...

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Publicat a:BMC Bioinformatics
Autors principals: Medo, Matúš, Aebersold, Daniel M., Medová, Michaela
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842221/
https://ncbi.nlm.nih.gov/pubmed/31706265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3144-3
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