Missing value imputation in proximity extension assay-based targeted proteomics data

Targeted proteomics utilizing antibody-based proximity extension assays provides sensitive and highly specific quantifications of plasma protein levels. Multivariate analysis of this data is hampered by frequent missing values (random or left censored), calling for imputation approaches. While appro...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lenz, Michael, Schulz, Andreas, Koeck, Thomas, Rapp, Steffen, Nagler, Markus, Sauer, Madeleine, Eggebrecht, Lisa, Ten Cate, Vincent, Panova-Noeva, Marina, Prochaska, Jürgen H., Lackner, Karl J., Münzel, Thomas, Leineweber, Kirsten, Wild, Philipp S., Andrade-Navarro, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735586/
https://ncbi.nlm.nih.gov/pubmed/33315883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243487
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