Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade

Immune checkpoint inhibitors are a powerful new tool in the treatment of cancer, with prolonged responses in multiple diseases, including hematologic malignancies, such as Hodgkin lymphoma. However, in a recent report, we demonstrated that the PD-1 inhibitor nivolumab led to rapid progression in pat...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Rauch, Daniel A., Conlon, Kevin C., Janakiram, Murali, Brammer, Jonathan E., Harding, John C., Ye, B. Hilda, Zang, Xingxing, Ren, Xiaoxin, Olson, Sydney, Cheng, Xiaogang, Miljkovic, Milos D., Sundaramoorthi, Hemalatha, Joseph, Ancy, Skidmore, Zachary L., Griffith, Obi, Griffith, Malachi, Waldmann, Thomas A., Ratner, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839957/
https://ncbi.nlm.nih.gov/pubmed/31467059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002038
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