Lobe specificity of iron binding to transferrin modulates murine erythropoiesis and iron homeostasis

Transferrin, the major plasma iron-binding molecule, interacts with cell-surface receptors to deliver iron, modulates hepcidin expression, and regulates erythropoiesis. Transferrin binds and releases iron via either or both of 2 homologous lobes (N and C). To test the hypothesis that the specificity...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Parrow, Nermi L., Li, Yihang, Feola, Maria, Guerra, Amaliris, Casu, Carla, Prasad, Princy, Mammen, Luke, Ali, Faris, Vaicikauskas, Edvinas, Rivella, Stefano, Ginzburg, Yelena Z., Fleming, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2019
Fag:
Plenary Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839954/
https://ncbi.nlm.nih.gov/pubmed/31434707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018893099
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