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Coadministration of kla peptide with HPRP-A1 to enhance anticancer activity

The apoptosis-inducing peptide kla (KLAKLAK)(2) possesses the ability to disrupt mitochondrial membranes and induce cancer cell apoptosis, but this peptide has a poor eukaryotic cell-penetrating potential. Thus, it requires the assistance of other peptides for effective translocation at micromolar c...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Hao, Wenjing, Hu, Cuihua, Huang, Yibing, Chen, Yuxin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839859/
https://ncbi.nlm.nih.gov/pubmed/31703065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223738
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