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Mass Spectrometry Fingerprints of Small-Molecule Metabolites in Biofluids: Building a Spectral Library of Recurrent Spectra for Urine Analysis

A large fraction of ions observed in electrospray liquid chromatography–mass spectrometry (LC–ESI-MS) experiments of biological samples remain unidentified. One of the main reasons for this is that spectral libraries of pure compounds fail to account for the complexity of the metabolite profiling of...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Simón-Manso, Yamil, Marupaka, Ramesh, Yan, Xinjian, Liang, Yuxue, Telu, Kelly H., Mirokhin, Yuri, Stein, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839828/
https://ncbi.nlm.nih.gov/pubmed/31424920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b02977
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