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Periodic Oxaliplatin Administration in Synergy with PER2‐Mediated PCNA Transcription Repression Promotes Chronochemotherapeutic Efficacy of OSCC

Developing chemotherapeutic resistance affects clinical outcomes of oxaliplatin treatment on various types of cancer. Thus, it is imperative to explore alternative therapeutic strategies to improve the efficacy of oxaliplatin. Here, it is shown that circadian regulator period 2 (PER2) can potentiate...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Tang, Qingming, Xie, Mengru, Yu, Shaoling, Zhou, Xin, Xie, Yanling, Chen, Guangjin, Guo, Fengyuan, Chen, Lili
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839751/
https://ncbi.nlm.nih.gov/pubmed/31728273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201900667
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