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Feedback-Driven Assembly of the Axon Initial Segment

The axon initial segment (AIS) is a unique neuronal compartment that plays a crucial role in the generation of action potential and neuronal polarity. The assembly of the AIS requires membrane, scaffolding, and cytoskeletal proteins, including Ankyrin-G and TRIM46. How these components cooperate in...

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Dettagli Bibliografici
Pubblicato in:Neuron
Autori principali: Fréal, Amélie, Rai, Dipti, Tas, Roderick P., Pan, Xingxiu, Katrukha, Eugene A., van de Willige, Dieudonnée, Stucchi, Riccardo, Aher, Amol, Yang, Chao, Altelaar, A.F. Maarten, Vocking, Karin, Post, Jan Andries, Harterink, Martin, Kapitein, Lukas C., Akhmanova, Anna, Hoogenraad, Casper C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839619/
https://ncbi.nlm.nih.gov/pubmed/31474508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.07.029
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