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Feedback-Driven Assembly of the Axon Initial Segment

The axon initial segment (AIS) is a unique neuronal compartment that plays a crucial role in the generation of action potential and neuronal polarity. The assembly of the AIS requires membrane, scaffolding, and cytoskeletal proteins, including Ankyrin-G and TRIM46. How these components cooperate in...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Fréal, Amélie, Rai, Dipti, Tas, Roderick P., Pan, Xingxiu, Katrukha, Eugene A., van de Willige, Dieudonnée, Stucchi, Riccardo, Aher, Amol, Yang, Chao, Altelaar, A.F. Maarten, Vocking, Karin, Post, Jan Andries, Harterink, Martin, Kapitein, Lukas C., Akhmanova, Anna, Hoogenraad, Casper C.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839619/
https://ncbi.nlm.nih.gov/pubmed/31474508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.07.029
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