Midlife Insulin Resistance as a Predictor for Late-Life Cognitive Function and Cerebrovascular Lesions

BACKGROUND: Type 2 diabetes (T2DM) increases the risk for Alzheimer’s disease (AD) but not for AD neuropathology. The association between T2DM and AD is assumed to be mediated through vascular mechanisms. However, insulin resistance (IR), the hallmark of T2DM, has been shown to associate with AD neu...

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Bibliografische gegevens
Gepubliceerd in:J Alzheimers Dis
Hoofdauteurs: Toppala, Sini, Ekblad, Laura L., Lötjönen, Jyrki, Helin, Semi, Hurme, Saija, Johansson, Jarkko, Jula, Antti, Karrasch, Mira, Koikkalainen, Juha, Laine, Hanna, Parkkola, Riitta, Viitanen, Matti, Rinne, Juha O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: IOS Press 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839606/
https://ncbi.nlm.nih.gov/pubmed/31561373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190691
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