CRUP: a comprehensive framework to predict condition-specific regulatory units

We present the software Condition-specific Regulatory Units Prediction (CRUP) to infer from epigenetic marks a list of regulatory units consisting of dynamically changing enhancers with their target genes. The workflow consists of a novel pre-trained enhancer predictor that can be reliably applied a...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Ramisch, Anna, Heinrich, Verena, Glaser, Laura V., Fuchs, Alisa, Yang, Xinyi, Benner, Philipp, Schöpflin, Robert, Li, Na, Kinkley, Sarah, Römer-Hillmann, Anja, Longinotto, John, Heyne, Steffen, Czepukojc, Beate, Kessler, Sonja M., Kiemer, Alexandra K., Cadenas, Cristina, Arrigoni, Laura, Gasparoni, Nina, Manke, Thomas, Pap, Thomas, Pospisilik, John A., Hengstler, Jan, Walter, Jörn, Meijsing, Sebastiaan H., Chung, Ho-Ryun, Vingron, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839171/
https://ncbi.nlm.nih.gov/pubmed/31699133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1860-7
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