Liver-expressed antimicrobial peptide 2 antagonizes the effect of ghrelin in rodents

Ghrelin, a stomach-derived peptide, promotes feeding and growth hormone (GH) secretion. A recent study identified liver-expressed antimicrobial peptide 2 (LEAP2) as an endogenous inhibitor of ghrelin-induced GH secretion, but the effect of LEAP2 in the brain remained unknown. In this study, we showe...

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Udgivet i:J Endocrinol
Main Authors: Islam, Md Nurul, Mita, Yuichiro, Maruyama, Keisuke, Tanida, Ryota, Zhang, Weidong, Sakoda, Hideyuki, Nakazato, Masamitsu
Format: Artigo
Sprog:Inglês
Udgivet: Bioscientifica Ltd 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839046/
https://ncbi.nlm.nih.gov/pubmed/31539874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-19-0102
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