DeepHLApan: A Deep Learning Approach for Neoantigen Prediction Considering Both HLA-Peptide Binding and Immunogenicity

Neoantigens play important roles in cancer immunotherapy. Current methods used for neoantigen prediction focus on the binding between human leukocyte antigens (HLAs) and peptides, which is insufficient for high-confidence neoantigen prediction. In this study, we apply deep learning techniques to pre...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Wu, Jingcheng, Wang, Wenzhe, Zhang, Jiucheng, Zhou, Binbin, Zhao, Wenyi, Su, Zhixi, Gu, Xun, Wu, Jian, Zhou, Zhan, Chen, Shuqing
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838785/
https://ncbi.nlm.nih.gov/pubmed/31736974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02559
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