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High-throughput stability screening of neoantigen/HLA complexes improves immunogenicity predictions
Mutated peptides (neoantigens) from a patient’s cancer genome can serve as targets for T-cell immunity, but identifying which peptides can be presented by an MHC molecule and elicit T cells has been difficult. Although algorithms that predict MHC binding exist, they are not yet able to distinguish e...
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| Publicado no: | Cancer Immunol Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6324732/ https://ncbi.nlm.nih.gov/pubmed/30425106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0395 |
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