Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to be defined. We demonstrate here that selective...

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Vydáno v:eLife
Hlavní autoři: Rajbhandari, Prashant, Arneson, Douglas, Hart, Sydney K, Ahn, In Sook, Diamante, Graciel, Santos, Luis C, Zaghari, Nima, Feng, An-Chieh, Thomas, Brandon J, Vergnes, Laurent, Lee, Stephen D, Rajbhandari, Abha K, Reue, Karen, Smale, Stephen T, Yang, Xia, Tontonoz, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837845/
https://ncbi.nlm.nih.gov/pubmed/31644425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49501
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