Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy

Malignant mesothelioma (MM) is a fatal neoplastic disease with no therapeutic option. Therefore, the search for novel therapies is of paramount importance. Methods Since mitochondrial targeting of α-tocopheryl succinate (α-TOS) by its tagging with triphenylphosphonium enhances its cytotoxic effects...

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Detalles Bibliográficos
Publicado en:Redox Rep
Autores principales: Kovarova, Jaromira, Bajzikova, Martina, Vondrusova, Magdalena, Stursa, Jan, Goodwin, Jacob, Nguyen, Maria, Zobalova, Renata, Pesdar, Elham Alizadeh, Truksa, Jaroslav, Tomasetti, Marco, Dong, Lan-Feng, Neuzil, Jiri
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2013
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837448/
https://ncbi.nlm.nih.gov/pubmed/24225203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/1351000213Y.0000000064
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