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Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention

Efficient clearance of transformed cells by Natural Killer (NK) cells is regulated by several activating receptors, including NKG2D, NCRs, and DNAM-1. Expression of these receptors as well as their specific “induced self” ligands is finely regulated during malignant transformation through the integr...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Molfetta, Rosa, Zingoni, Alessandra, Santoni, Angela, Paolini, Rossella
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836727/
https://ncbi.nlm.nih.gov/pubmed/31736972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02557
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