Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer

BACKGROUND: The tumor microenvironment (TME) combines features of regulatory cytokines and immune cell populations to evade the recognition by the immune system. Myeloid-derived suppressor cells (MDSC) comprise populations of immature myeloid cells in tumor-bearing hosts with a highly immunosuppress...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Autores principales: Metzger, Philipp, Kirchleitner, Sabrina V., Kluge, Michael, Koenig, Lars M., Hörth, Christine, Rambuscheck, Carlotta A., Böhmer, Daniel, Ahlfeld, Julia, Kobold, Sebastian, Friedel, Caroline C., Endres, Stefan, Schnurr, Max, Duewell, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836385/
https://ncbi.nlm.nih.gov/pubmed/31694706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0778-7
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