Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

BACKGROUND: Genetic factors, dysregulation in the endocrine system, cytokine and paracrine factors are implicated in the pathogenesis of familial short stature (FSS). Nowadays, the treatment choice for FSS is limited, with only recombinant human growth hormone (rhGH) being available. METHODS: Herein...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Wong, Henry Sung-Ching, Lin, Ying-Ju, Lu, Hsing-Fang, Liao, Wen-Ling, Chen, Chien-Hsiun, Wu, Jer-Yuarn, Chang, Wei-Chiao, Tsai, Fuu-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836357/
https://ncbi.nlm.nih.gov/pubmed/31699087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-019-0581-2
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