GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients

BACKGROUND: In breast cancer, activation of bone morphogenetic protein (BMP) signaling and elevated levels of BMP-antagonists have been linked to tumor progression and metastasis. However, the simultaneous upregulation of BMPs and their antagonist, and the fact that both promote tumor aggressiveness...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Neckmann, Ulrike, Wolowczyk, Camilla, Hall, Martina, Almaas, Eivind, Ren, Jiang, Zhao, Sen, Johannessen, Bjarne, Skotheim, Rolf I., Bjørkøy, Geir, Dijke, Peter ten, Holien, Toril
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836336/
https://ncbi.nlm.nih.gov/pubmed/31694641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0467-7
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