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Gelatin-Alginate Complexes for EGF Encapsulation: Effects of H-Bonding and Electrostatic Interactions

Gelatin Type A (GA) and sodium alginate (SA) complexes were explored to encapsulate epidermal growth factor (EGF), and thereby to circumvent its proteolytic degradation upon topical application to chronic wounds. Phase diagrams were constructed based on turbidity as a function of GA to SA ratio and...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Jeong, Seonghee, Kim, ByungWook, Lau, Hui-Chong, Kim, Aeri
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835588/
https://ncbi.nlm.nih.gov/pubmed/31614977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11100530
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