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Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs

Amyotrophic lateral sclerosis (ALS) is a complex and fatal neurodegenerative disease for which the causes of disease onset and progression remain unclear. Recent advances in human induced pluripotent stem cell (hiPSC)-based models permit the study of the genetic factors associated with ALS in patien...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: Halpern, Madeline, Brennand, Kristen J., Gregory, James
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834907/
https://ncbi.nlm.nih.gov/pubmed/31381978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104562
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