Structural analysis of human SEPHS2 protein, a selenocysteine machinery component, over-expressed in triple negative breast cancer

Selenophosphate synthetase 2 (SEPHS2) synthesizes selenide and ATP into selenophosphate, the selenium donor for selenocysteine (Sec), which is cotranslationally incorporated into selenoproteins. The action and regulatory mechanisms of SEPHS2 as well as its role in carcinogenesis (especially breast c...

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Publicado en:Sci Rep
Autores principales: Nunziata, Carmine, Polo, Andrea, Sorice, Angela, Capone, Francesca, Accardo, Marina, Guerriero, Eliana, Marino, Federica Zito, Orditura, Michele, Budillon, Alfredo, Costantini, Susan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834634/
https://ncbi.nlm.nih.gov/pubmed/31695102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52718-0
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