Structural analysis of human SEPHS2 protein, a selenocysteine machinery component, over-expressed in triple negative breast cancer

Selenophosphate synthetase 2 (SEPHS2) synthesizes selenide and ATP into selenophosphate, the selenium donor for selenocysteine (Sec), which is cotranslationally incorporated into selenoproteins. The action and regulatory mechanisms of SEPHS2 as well as its role in carcinogenesis (especially breast c...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Nunziata, Carmine, Polo, Andrea, Sorice, Angela, Capone, Francesca, Accardo, Marina, Guerriero, Eliana, Marino, Federica Zito, Orditura, Michele, Budillon, Alfredo, Costantini, Susan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834634/
https://ncbi.nlm.nih.gov/pubmed/31695102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52718-0
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