Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload

Heart failure is associated with profound alterations of energy metabolism thought to play a major role in the progression of this syndrome. SIRT1 is a metabolic sensor of cellular energy and exerts essential functions on energy metabolism, oxidative stress response, apoptosis, or aging. Importantly...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sanz, Maria-Nieves, Grimbert, Lucile, Moulin, Maryline, Gressette, Mélanie, Rucker-Martin, Catherine, Lemaire, Christophe, Mericskay, Mathias, Veksler, Vladimir, Ventura-Clapier, Renée, Garnier, Anne, Piquereau, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834316/
https://ncbi.nlm.nih.gov/pubmed/31658614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205005
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