Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload

Heart failure is associated with profound alterations of energy metabolism thought to play a major role in the progression of this syndrome. SIRT1 is a metabolic sensor of cellular energy and exerts essential functions on energy metabolism, oxidative stress response, apoptosis, or aging. Importantly...

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Sanz, Maria-Nieves, Grimbert, Lucile, Moulin, Maryline, Gressette, Mélanie, Rucker-Martin, Catherine, Lemaire, Christophe, Mericskay, Mathias, Veksler, Vladimir, Ventura-Clapier, Renée, Garnier, Anne, Piquereau, Jérôme
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834316/
https://ncbi.nlm.nih.gov/pubmed/31658614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205005
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