Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs

The genome of Mycobacterium tuberculosis (Mtb) encodes three β-carbonic anhydrases (CAs, EC 4.2.1.1) that are crucial for the life cycle of the bacterium. The Mtb β-CAs have been cloned and characterized, and the catalytic activities of the enzymes have been studied. The crystal structures of two of...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Aspatwar, Ashok, Kairys, Visvaldas, Rala, Sangeetha, Parikka, Mataleena, Bozdag, Murat, Carta, Fabrizio, Supuran, Claudiu T., Parkkila, Seppo
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834203/
https://ncbi.nlm.nih.gov/pubmed/31627429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205153
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