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The Involvement of the RhoA/ROCK Signaling Pathway in Hypersensitivity Reactions Induced by Paclitaxel Injection

A high incidence of hypersensitivity reactions (HSRs) largely limits the use of paclitaxel injection. Currently, these reactions are considered to be mediated by histamine release and complement activation. However, the evidence is insufficient and the molecular mechanism involved in paclitaxel inje...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Pan, Chen, Zhang, Yu-Shi, Han, Jia-Yin, Li, Chun-Ying, Yi, Yan, Zhao, Yong, Wang, Lian-Mei, Tian, Jing-Zhuo, Liu, Su-Yan, Li, Gui-Qin, Li, Xiao-Long, Xian, Zhong, Liang, Ai-Hua
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834182/
https://ncbi.nlm.nih.gov/pubmed/31600977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20204988
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