Mixed-Generation PAMAM G3-G0 Megamer as a Drug Delivery System for Nimesulide: Antitumor Activity of the Conjugate Against Human Squamous Carcinoma and Glioblastoma Cells

Polyhydroxylated dendrimer was synthesized from poly(amidoamine) (PAMAM) dendrimer generation 3 by addition of glycidol (G3(gl)). G3(gl) megamer was further modified by binding PAMAM G0 dendrimers by activation of G3(gl) with p-nitrophenylchloroformate, followed by the addition of excess PAMAM G0 an...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Zaręba, Magdalena, Sareło, Przemysław, Kopaczyńska, Marta, Białońska, Agata, Uram, Łukasz, Walczak, Małgorzata, Aebisher, David, Wołowiec, Stanisław
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834146/
https://ncbi.nlm.nih.gov/pubmed/31601050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20204998
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