Different patterns of nuclear and mitochondrial penetration by the G3 PAMAM dendrimer and its biotin–pyridoxal bioconjugate BC-PAMAM in normal and cancer cells in vitro

The intracellular localization and colocalization of a fluorescently labeled G3 amine-terminated cationic polyamidoamine (PAMAM) dendrimer and its biotin–pyridoxal (BC-PAMAM) bioconjugate were investigated in a concentration-dependent manner in normal human fibroblast (BJ) and squamous epithelial ca...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Uram, Łukasz, Szuster, Magdalena, Filipowicz, Aleksandra, Gargasz, Krzysztof, Wołowiec, Stanisław, Wałajtys-Rode, Elżbieta
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567239/
https://ncbi.nlm.nih.gov/pubmed/26379435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S87307
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