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Amylin’s effects against Aβ induced tauopathy and synapse loss in primary neurons

Recent studies demonstrate that peripheral amylin treatment reduces pathology in mouse models of Alzheimer’s disease (AD). However, soluble and aggregated amylin are distinct species; while amylin is a physiological neuropeptide, amylin aggregation is a pathological factor for diabetes. We thus hypo...

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Bibliografske podrobnosti
izdano v:J Alzheimers Dis
Main Authors: Gan, Qini, Yao, Hongbo, Na, Hana, Ballance, Heather, Tao, Qiushan, Leung, Lorene, Tian, Hua, Zhu, Haihao, Wolozin, Benjamin, Qiu, Wei Qiao
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833957/
https://ncbi.nlm.nih.gov/pubmed/31306122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190161
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