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Amylin and its analogs: a friend or foe for the treatment of Alzheimer's disease?
Amylin, a gut-brain axis hormone, and amyloid-beta peptides (Aβ), a major component of the Alzheimer's disease (AD) brain, share several features, including similar β-sheet secondary structures, binding to the same receptor and being degraded by the same protease, insulin degrading enzyme (IDE)...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114192/ https://ncbi.nlm.nih.gov/pubmed/25120481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00186 |
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