miR-16 regulates proliferation and invasion of lung cancer cells via the ERK/MAPK signaling pathway by targeted inhibition of MAPK kinase 1 (MEK1)

OBJECTIVE: The ERK/MAPK signaling pathway regulates cell proliferation and invasion. MAPK kinase 1 (MEK1) is a protein kinase upstream of ERK that can activate the pathway. Expression of microRNA (miR)-16 in lung cancer tissues is decreased. The aim of this study was to determine roles of miR-16 in...

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Udgivet i:J Int Med Res
Main Authors: Chen, TianMing, Xiao, Qi, Wang, XiaoJun, Wang, ZhongQiu, Hu, JingWen, Zhang, Zhi, Gong, ZhuNan, Chen, ShiLin
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2019
Fag:
Pre-Clinical Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833413/
https://ncbi.nlm.nih.gov/pubmed/31379227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060519856505
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