Pre-exposure prophylaxis differentially alters circulating and mucosal immune cell activation in HSV-2 seropositive women

OBJECTIVE: Oral tenofovir-based pre-exposure prophylaxis (PrEP) is an important tool for prevention of new HIV infections, which also reduces subclinical HSV-2 shedding and symptomatic lesions in HIV-negative, HSV-2-seropositive individuals. However, the impact of PrEP on mucosal immunity has not be...

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保存先:
書誌詳細
出版年:AIDS
主要な著者: RICHERT-SPUHLER, Laura E., PATTACINI, Laura, PLEWS, Margot, IRUNGU, Elizabeth, MUWONGE, Timothy R., KATABIRA, Elly, MUGO, Nelly, MEYERS, Adrienne F.A., CELUM, Connie, BAETEN, Jared M., LINGAPPA, Jairam R., LUND, Jennifer M.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832814/
https://ncbi.nlm.nih.gov/pubmed/31335802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002323
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