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Altered Dynamics of Canonical Feedback Inhibition Predicts Increased Burst Transmission in Chronic Epilepsy

Inhibitory interneurons, organized into canonical feedforward and feedback motifs, play a key role in controlling normal and pathological neuronal activity. We demonstrate prominent quantitative changes in the dynamics of feedback inhibition in a rat model of chronic epilepsy (male Wistar rats). Sys...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pothmann, Leonie, Klos, Christian, Braganza, Oliver, Schmidt, Sarah, Horno, Oihane, Memmesheimer, Raoul-Martin, Beck, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832680/
https://ncbi.nlm.nih.gov/pubmed/31519822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2594-18.2019
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