Impaired d-Serine-Mediated Cotransmission Mediates Cognitive Dysfunction in Epilepsy

The modulation of synaptic plasticity by NMDA receptor (NMDAR)-mediated processes is essential for many forms of learning and memory. Activation of NMDARs by glutamate requires the binding of a coagonist to a regulatory site of the receptor. In many forebrain regions, this coagonist is d-serine. Her...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Klatte, Katharina, Kirschstein, Timo, Otte, David, Pothmann, Leonie, Müller, Lorenz, Tokay, Tursonjan, Kober, Maria, Uebachs, Mischa, Zimmer, Andreas, Beck, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619718/
https://ncbi.nlm.nih.gov/pubmed/23926260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5423-12.2013
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