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An LTR retrotransposon‐derived lncRNA interacts with RNF169 to promote homologous recombination

LTR retrotransposons are abundant repetitive elements in the human genome, but their functions remain poorly understood. Here, we report the function and regulatory mechanism of an ERV‐9 LTR retrotransposon‐derived lncRNA called p53‐regulated lncRNA for homologous recombination (HR) repair 1 (PRLH1)...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Deng, Bing, Xu, Wenli, Wang, Zelin, Liu, Chang, Lin, Penghui, Li, Bin, Huang, Qiaojuan, Yang, Jianhua, Zhou, Hui, Qu, Lianghu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832013/
https://ncbi.nlm.nih.gov/pubmed/31486214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847650
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