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Properties of Samples With Segregating Polymerase Chain Reaction (PCR) Dropout Mutations Within a Species

In polymerase chain reaction (PCR)-based DNA sequencing studies, there is the possibility that mutations at the binding sites of primers result in no primer binding and therefore no amplification. In this article, we call such mutations PCR dropouts and present a coalescent-based theory of the distr...

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Vydáno v:Evol Bioinform Online
Hlavní autor: Griswold, Cortland K
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831972/
https://ncbi.nlm.nih.gov/pubmed/31723319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176934319883612
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