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Properties of Samples With Segregating Polymerase Chain Reaction (PCR) Dropout Mutations Within a Species

In polymerase chain reaction (PCR)-based DNA sequencing studies, there is the possibility that mutations at the binding sites of primers result in no primer binding and therefore no amplification. In this article, we call such mutations PCR dropouts and present a coalescent-based theory of the distr...

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Publicat a:Evol Bioinform Online
Autor principal: Griswold, Cortland K
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831972/
https://ncbi.nlm.nih.gov/pubmed/31723319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176934319883612
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