SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function

The NF-κB pathway is constitutively activated in adult T cell leukemia, an aggressive malignancy caused by Human T Leukemia Virus type 1 (HTLV-1). The viral oncoprotein Tax triggers this constitutive activation by interacting with the ubiquitin-rich IKK complex. We previously demonstrated that Optin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schwob, Aurélien, Teruel, Elodie, Dubuisson, Louise, Lormières, Florence, Verlhac, Pauline, Abudu, Yakubu Princely, Gauthier, Janelle, Naoumenko, Marie, Cloarec-Ung, Fanny-Meï, Faure, Mathias, Johansen, Terje, Dutartre, Hélène, Mahieux, Renaud, Journo, Chloé
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831704/
https://ncbi.nlm.nih.gov/pubmed/31690813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52408-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados