Maf1 ameliorates cardiac hypertrophy by inhibiting RNA polymerase III through ERK1/2

Rationale: An imbalance between protein synthesis and degradation is one of the mechanisms of cardiac hypertrophy. Increased transcription in cardiomyocytes can lead to excessive protein synthesis and cardiac hypertrophy. Maf1 is an RNA polymerase III (RNA pol III) inhibitor that plays a pivotal rol...

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Publicado en:Theranostics
Autores principales: Sun, Yu, Chen, Cong, Xue, Ruicong, Wang, Yan, Dong, Bin, Li, Jiayong, Chen, Chen, Jiang, Jingzhou, Fan, Wendong, Liang, Zhuomin, Huang, Huiling, Fang, Rong, Dai, Gang, Yan, Youchen, Yang, Tiqun, Li, Xiangxue, Huang, Zhan-Peng, Dong, Yugang, Liu, Chen
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831308/
https://ncbi.nlm.nih.gov/pubmed/31695767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33006
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