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The HSP90 inhibitor onalespib potentiates (177)Lu-DOTATATE therapy in neuroendocrine tumor cells

(177)Lu-DOTATATE was recently approved for the treatment of somatostatin receptor (SSTR)-positive neuroen-docrine tumors (NETs). However, despite impressive response rates, complete responses are rare. Heat shock protein 90 (HSP90) inhibitors have been suggested as suitable therapeutic agents for NE...

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Détails bibliographiques
Publié dans:Int J Oncol
Auteurs principaux: Lundsten, Sara, Spiegelberg, Diana, Stenerlöw, Bo, Nestor, Marika
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831206/
https://ncbi.nlm.nih.gov/pubmed/31638190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4888
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