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Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the “von Magnus effect”
Continuous cell culture-based influenza vaccine production could significantly reduce footprint and manufacturing costs compared to current batch processing. However, yields of influenza virus in continuous mode can be affected by oscillations in virus titers caused by periodic accumulation of defec...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6830746/ https://ncbi.nlm.nih.gov/pubmed/31689309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224317 |
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