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GLUCOCORTICOIDS INHIBIT NOTCH TARGET GENE EXPRESSION IN OSTEOBLASTS

Glucocorticoids in excess suppress osteoblast function and cause osteoporosis. We demonstrated that cortisol induces the expression of selected Notch receptors in osteoblasts, revealing a potential mechanism for the skeletal effects of glucocorticoids. However, it remains to be determined whether in...

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Bibliografiske detaljer
Udgivet i:J Cell Biochem
Main Authors: Zanotti, Stefano, Yu, Jungeun, Adhikari, Suyash, Canalis, Ernesto
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830575/
https://ncbi.nlm.nih.gov/pubmed/29575203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26798
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