Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice

LCZ696 (sacubitril/valsartan) is an angiotensin receptor-neprilysin inhibitor and has shown beneficial effects in patients with heart failure. However, whether LCZ696 protects against left atrial (LA) and LA appendage (LAA) dysfunction is still unclear. The present study aimed to assess the efficacy...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Suo, Ya, Yuan, Meng, Li, Hongmin, Zhang, Yue, Li, Ying, Fu, Huaying, Han, Fei, Ma, Changhui, Wang, Yuanyuan, Bao, Qiankun, Li, Guangping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830387/
https://ncbi.nlm.nih.gov/pubmed/31736759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01285
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