Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice

LCZ696 (sacubitril/valsartan) is an angiotensin receptor-neprilysin inhibitor and has shown beneficial effects in patients with heart failure. However, whether LCZ696 protects against left atrial (LA) and LA appendage (LAA) dysfunction is still unclear. The present study aimed to assess the efficacy...

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Vydáno v:Front Pharmacol
Hlavní autoři: Suo, Ya, Yuan, Meng, Li, Hongmin, Zhang, Yue, Li, Ying, Fu, Huaying, Han, Fei, Ma, Changhui, Wang, Yuanyuan, Bao, Qiankun, Li, Guangping
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830387/
https://ncbi.nlm.nih.gov/pubmed/31736759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01285
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