Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice

LCZ696 (sacubitril/valsartan) is an angiotensin receptor-neprilysin inhibitor and has shown beneficial effects in patients with heart failure. However, whether LCZ696 protects against left atrial (LA) and LA appendage (LAA) dysfunction is still unclear. The present study aimed to assess the efficacy...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Suo, Ya, Yuan, Meng, Li, Hongmin, Zhang, Yue, Li, Ying, Fu, Huaying, Han, Fei, Ma, Changhui, Wang, Yuanyuan, Bao, Qiankun, Li, Guangping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830387/
https://ncbi.nlm.nih.gov/pubmed/31736759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01285
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