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A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD), an increasingly prevalent and underdiagnosed disease, is postulated to be caused by hepatic fat mediated pathological mechanisms. Mitochondrial dysfunction is proposed to be involved, but it is not known whether this is a pathological driver or a consequenc...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Malik, Afshan N, Simões, Inês C.M., Rosa, Hannah S., Khan, Safa, Karkucinska-Wieckowska, Agnieszka, Wieckowski, Mariusz R.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830072/
https://ncbi.nlm.nih.gov/pubmed/31597406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101222
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