Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling

Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments. These applications are, however, limited in their capacity to generate functional hepatocytes in a reproducible and efficient manner. Here, we generated and charac...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Akbari, Soheil, Sevinç, Gülben Gürhan, Ersoy, Nevin, Basak, Onur, Kaplan, Kubra, Sevinç, Kenan, Ozel, Erkin, Sengun, Berke, Enustun, Eray, Ozcimen, Burcu, Bagriyanik, Alper, Arslan, Nur, Önder, Tamer Tevfik, Erdal, Esra
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829764/
https://ncbi.nlm.nih.gov/pubmed/31522975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.08.007
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