Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes

In patients with inactivating mutations in myosin Vb (Myo5B), enterocytes show large inclusions lined by microvilli. The origin of inclusions in small-intestinal enterocytes in microvillus inclusion disease is currently unclear. We postulated that inclusions in Myo5b KO mouse enterocytes form throug...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Engevik, Amy C., Kaji, Izumi, Postema, Meagan M., Faust, James J., Meyer, Anne R., Williams, Janice A., Fitz, Gillian N., Tyska, Matthew J., Wilson, Jean M., Goldenring, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829668/
https://ncbi.nlm.nih.gov/pubmed/31562230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902063
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