Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes

In patients with inactivating mutations in myosin Vb (Myo5B), enterocytes show large inclusions lined by microvilli. The origin of inclusions in small-intestinal enterocytes in microvillus inclusion disease is currently unclear. We postulated that inclusions in Myo5b KO mouse enterocytes form throug...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Engevik, Amy C., Kaji, Izumi, Postema, Meagan M., Faust, James J., Meyer, Anne R., Williams, Janice A., Fitz, Gillian N., Tyska, Matthew J., Wilson, Jean M., Goldenring, James R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829668/
https://ncbi.nlm.nih.gov/pubmed/31562230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902063
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