Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes

In patients with inactivating mutations in myosin Vb (Myo5B), enterocytes show large inclusions lined by microvilli. The origin of inclusions in small-intestinal enterocytes in microvillus inclusion disease is currently unclear. We postulated that inclusions in Myo5b KO mouse enterocytes form throug...

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Vydáno v:J Cell Biol
Hlavní autoři: Engevik, Amy C., Kaji, Izumi, Postema, Meagan M., Faust, James J., Meyer, Anne R., Williams, Janice A., Fitz, Gillian N., Tyska, Matthew J., Wilson, Jean M., Goldenring, James R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829668/
https://ncbi.nlm.nih.gov/pubmed/31562230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902063
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