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Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease
Microvillus inclusion disease (MVID) is a severe form of congenital diarrhea that arises from inactivating mutations in the gene encoding myosin Vb (MYO5B). We have examined the association of mutations in MYO5B and disruption of microvillar assembly and polarity in enterocytes. Stable MYO5B knockdo...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071383/ https://ncbi.nlm.nih.gov/pubmed/24892806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71651 |
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