Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection

Background: Schistosomiasis is an immunopathogenic disease in which Th17 cells play vital roles. Hepatic granuloma formation and subsequent fibrosis are its main pathologic manifestations and the leading causes of hepatic cirrhosis, and effective therapeutic interventions are lacking. In this study,...

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I publikationen:Cells
Huvudupphovsmän: Zhou, Wei, Yang, Yingying, Mei, Congjin, Dong, Panpan, Mu, Shasha, Wu, Hongchu, Zhou, Yonghua, Zheng, Yi, Guo, Fukun, Yang, Jun-Qi
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829618/
https://ncbi.nlm.nih.gov/pubmed/31623153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101262
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